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ANTIHYPERLIPIDEMIA AGENTS Plasma lipids Transported in bloodstream in form of macromolecular complexes of lipid and known as lipoproteins Two major clinical importance/sequelae of high lipid Acute pancreatitis atherosclerosis Hyperlipoproteinemia Hyperlipidemia Lipoprotein disorders Primary hypertriglyceridemias Primary chylomicronemia Familial hypertriglyceridemia Familial combined hyperlipoproteinemia Familial dysbetalipoproteinemia Primary hypercholesterolemias Famimial hypercholesterolemia Familial ligan-defective apolipoprotein B Familial combine hyperlipoproteinemia Lp(a) hyperlipoproteinemia Secondary hyperlipoproteinemia Lipid-lowering drugs Several drugs are used To decrease plasma LDL-cholesterol Drug therapy is only one approach Dietary measures are the first [...] | 19th January, 2010 | More News
antihyperlipidemia agents
ANTIHYPERLIPIDEMIA AGENTS
Plasma lipids
Transported in bloodstream in form of macromolecular complexes of lipid and known as lipoproteins
Two major clinical importance/sequelae of high lipid
Acute pancreatitis
atherosclerosis
Hyperlipoproteinemia
Hyperlipidemia
Lipoprotein disorders
Primary hypertriglyceridemias
Primary chylomicronemia
Familial hypertriglyceridemia
Familial combined hyperlipoproteinemia
Familial dysbetalipoproteinemia
Primary hypercholesterolemias
Famimial hypercholesterolemia
Familial ligan-defective apolipoprotein B
Familial combine hyperlipoproteinemia
Lp(a) hyperlipoproteinemia
Secondary hyperlipoproteinemia
Lipid-lowering drugs
Several drugs are used
To decrease plasma LDL-cholesterol
Drug therapy is only one approach
Dietary measures are the first [...]
Drug clearance
Clearance is the important factor determine drug concentration
Three factors that influence clearance
Dose
Organ blood flow
Intrinsic function of the liver or kidneys
Volume of distribution per se has no effect on clearance or on average steady-state blood levels.
[...]
Generic name
Generic name, drug: The term “generic name” has several meanings as regards drugs:
1. The chemical name of a drug.
2. A term referring to the chemical makeup of a drug rather than to the advertised brand name under which the drug is sold.
3. A term referring to any drug marketed under its chemical name without advertising.
In other words:
Generic drugs [...]
Pharmacology test 2
1. Direct-acting cholinergic drugs is/are:
a. Acetylcholine
b. Bethanecol
c. Carbachol
d. Pilocarpine
e. Nicotine
(TTTTT)
2. Indirect-acting cholinergic drugs is/are:
a. Edrohonium
b. Neostigmine
c. Physostigmine
d. Pyridostigmine
e. Parathion (Organophosphate)
[...]
Pharmacology test
Pharmacology test (3/11/2009)
1. Below are the factors that are contributed for the route of drug administration:
i. Rate and extent of absorption of the drug from different routes
ii. Rapidity with which the response is desired.
iii. Condition of the patient
iv. Physical and chemical properties of the drug
v. Site of desired action for example local or generalized anesthesia
a. (i) only
b. (i) and (ii)
c. (i) and (iv)
d. (iii), (iv) [...]

