http://www.ekaji4u.com Enrich Research Knowledge & Collaboration Tue, 19 Jan 2010 13:35:12 +0000 http://backend.userland.com/rss092 en ANTIHYPERLIPIDEMIA AGENTS Plasma lipids Transported in bloodstream in form of macromolecular complexes of lipid and known as lipoproteins Two major clinical importance/sequelae of high lipid Acute pancreatitis atherosclerosis Hyperlipoproteinemia Hyperlipidemia Lipoprotein disorders Primary hypertriglyceridemias Primary chylomicronemia Familial hypertriglyceridemia Familial combined hyperlipoproteinemia Familial dysbetalipoproteinemia Primary hypercholesterolemias Famimial hypercholesterolemia Familial ligan-defective apolipoprotein B Familial combine hyperlipoproteinemia Lp(a) hyperlipoproteinemia Secondary hyperlipoproteinemia Lipid-lowering drugs Several drugs are used To decrease plasma LDL-cholesterol Drug therapy is only one ... http://www.ekaji4u.com/antihyperlipidemia-agents Clearance is the important factor determine drug concentration Three factors that influence clearance Dose Organ blood flow Intrinsic function of the liver or kidneys Volume of distribution per se has no effect on clearance or on average steady-state blood levels. http://www.ekaji4u.com/drug-clearance Generic name, drug: The term "generic name" has several meanings as regards drugs: 1. The chemical name of a drug. 2. A term referring to the chemical makeup of a drug rather than to the advertised brand name under which the drug is sold. 3. A term referring to any drug marketed under ... http://www.ekaji4u.com/generic-name 1. Direct-acting cholinergic drugs is/are: a. Acetylcholine b. Bethanecol c. Carbachol d. Pilocarpine e. Nicotine (TTTTT) 2. Indirect-acting cholinergic drugs is/are: a. Edrohonium b. Neostigmine c. Physostigmine d. Pyridostigmine e. Parathion (Organophosphate) ... http://www.ekaji4u.com/pharmacology-test-2 Pharmacology test (3/11/2009) 1. Below are the factors that are contributed for the route of drug administration: i. Rate and extent of absorption of the drug from different routes ii. Rapidity with which the response is desired. iii. Condition of the patient iv. Physical and chemical properties of the drug v. Site of desired action for example local or generalized anesthesia a. (i) only b. (i) ... http://www.ekaji4u.com/pharmacology-test